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KMID : 0387720120230030267
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Korean Journal of Blood Transfusion
2012 Volume.23 No. 3 p.267 ~ p.271
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A First Experience of Rh(D) Incompatible Living Related Liver Transplantation in Korea
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Lee Seung-Hee
Chu Chong-Woo
Yang Kwang-Ho
Ryu Je-Ho
Moon Ki-Myung
Kim Hyung-Hoi
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Abstract
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To expand the indications for living liver allograft, an increasing number of clinical trials of ABO incompatible
liver transplantation have been reported in the literature. Administration of immunosuppressive drugs has resulted
in decreased rates of mortality and graft loss in patients undergoing in ABO-incompatible living donor liver
transplantation (LDLT). Rh incompatibility in liver transplantation has not been reported as frequently as that of
ABO-incompatible LDLT. Rh-antigens are said to be located only on red blood cells, and have not been demonstrated
on leukocytes or tissue cells. For this reason, the incompatibility of Rh antigen between the donor and
the recipient has received significantly less consideration in organ transplantations. Here, we report on a case of
Rh incompatible living related liver transplantation from a group O, Rh-positive donor to a group O, Rh-negative
recipient. The recipient did not develop Rh alloimmunization after administration of immunosupressive drugs and
Rh immunoglobin (RhIG).
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KEYWORD
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RH incompatible, Liver transplantation, Living donor, Alloimmunization, Anti-D
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